If this message does not disappear in a few seconds then you probably do not have JavaScript enabled on your browser. This calculator requires JavaScript to run. Depending on your browser settings, you may see a warning box at the top or bottom of the screen that says that this page is attempting to run ActiveX code. You should click to allow this page to run.


* All values of MAP less than 8 cmH2O (or less than 10 cmH2O **) are considered to be 8 cmH2O (or 10**) for purposes of the PedVAE definition. So for MAP values entered as less than or equal to 8 (or 10**) cmH2O, an increase in the daily minimum MAP to at least 12 cmH2O (or 14**), sustained for 2 or more calendar days, is required to meet the PedVAE definition.
** 10 for patients greater than or equal to 30 days



Message Box Error!

(Hint: this box is movable by dragging with your mouse. If you move it to one side and leave it open, the explanation will automatically update itself as things change.)

Question Yes
Criterion 1. Positive culture of one of the following (without requirement for purulent respiratory secretions):
  • Endotracheal aspirate ≥ 105 cfu/ml*
  • Bronchoalveolar lavage ≥ 104 cfu/ml*
  • Lung tissue ≥ 104 cfu/ml*
  • Protected specimen brush ≥ 103 cfu/ml*
*or corresponding semi-quantitative result
Criterion 2. Positive culture of one of the following (qualitative or quantitative/semi-quantitative culture without sufficient growth to meet Criterion 1).
  • Sputum
  • Endotracheal aspirate
  • Bronchoalveolar lavage
  • Lung tissue
  • Protected specimen brush

Evidence of purulent respiratory secretions (defined as secretions from lungs, bronchi or trachea that contain ≥ 25 neutrophils and ≤ 10 squamous epithelial cells).

Criterion 3. One of the following positive tests (as outlined in the protocol):
  • Pleural fluid culture
  • Lung histopathology
  • Diagnostic test for Legionella species
  • Diagnostic test for influenza virus, respiratory syncytial virus, adenovirus, parainfluenza virus, rhinovirus, human metapneumovirus or coronavirus.